hERG potassium channel inhibition by ivabradine may contribute to QT prolongation and risk of torsades de pointes.

نویسندگان

  • Jules C Hancox
  • Dario Melgari
  • Christopher E Dempsey
  • Kieran E Brack
  • John Mitcheson
  • G André Ng
چکیده

1 School of Physiology & Pharmacology, Medical Sciences Building, University Walk, Bristol, BS8 1TD. UK 2 School.of.Biochemistry, Medical Sciences Building, University Walk, Bristol, BS8 1TD, UK 3 Department of Cardiovascular Sciences, Cardiology group, University of Leicester, Glenfield Hospital, Leicester, LE3 9QP, UK 4 Department.of.Cell.Physiology.and.Pharmacology, Maurice Shock Medical Sciences Building, University Road, PO Box 138, Leicester, LE1 9HN, UK 5 NIHR.Leicester.Cardiovascular.Biomedical.Research.Unit, Leicester, LE3 9QP, UK

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عنوان ژورنال:
  • Therapeutic advances in drug safety

دوره 6 4  شماره 

صفحات  -

تاریخ انتشار 2015